生物利用度英文?bioavailability 生物利用度;生物藥效率 bioavailable 生物及生物藥效應的 cavaillon 卡維雍(法國地名)countervail 抵銷;補償;對抗 paravail 最低租戶 prevail獲勝,流行 travail職業勞動就業打工 trouvaille 新發現,新發明;獨特的想法;意外所得 unavailable 不能利用的,那么,生物利用度英文?一起來了解一下吧。
目錄
1拼音
2英文參考
3注解
1拼音
yào wù xī shōu
2英文參考
drug absorption
3注解
藥物吸收入體循環的速率和量被稱為生物利用度。它與許多因素有關,包括藥物自身劑型和工藝,理化性質及用藥個體的生理狀態。
藥廠生產出具有準確劑量的劑型,如片劑、膠囊劑、栓劑、透皮敷料或溶劑,這些制劑中,藥物常常與其他成分共存。如片劑中,藥物常常和稀釋劑、穩定劑、崩解劑和潤滑劑等附加成分組成混合物。這些混合物被碾碎并壓制成片。附加成分的種類、數量及壓制的程度均影響片劑溶解速度。要調整好各成分比例以優化藥物吸收速率和吸收程度。
如果片劑溶解和釋放藥物太快,就可能造成瞬時的藥物濃度過高而誘發藥物過量反應。在另一方面,如果片劑不溶解且釋放藥物不夠迅速,多數藥物可能隨糞便排出體外而影響機體吸收。腹瀉使藥物快速通過胃腸道,吸收減少。因此,食物、其他藥物及胃腸道病變都可影響藥物的生物利用度。
同一藥品應該具有相同生物利用度。但由于廠家不同,雖然藥物所含活性成分一樣,可因含非活性成分的差異而影響藥物的吸收。因此不同廠家生產的同一藥物,即便使用同一劑量,也可能藥效并不相同。當藥物制劑含有相同的活性成分,而且實際用藥后在相同時間有相同的血藥濃度時稱這些藥品生物等效。
http://www.moh.gov.cn/uploadfile/200662153858558.doc
牙菌斑:plaque (疾病及健康詞匯: http://www.geocities.jp/ps_dictionary/medical2/102.htm)
牙齦炎癥gingivitis
牙齦指數gingivitis index
牙齦出血指數(bleeding index,BI):
檢測標準testing standard
適用范圍Application scope
牙膏toothpaste
漱口水Mouthwash(Gargle, Dental water也可以的)
制定本標準所參考的文獻和標準Reference and criteria
臨床試驗clinical trial
活性成分Active Ingredients
一般原則”(general principles)
患者 suffers
control對照
隨機randomization
盲法(Blind Method)
Stratified method分層
功效應Effect
口腔護理用品Oral & dental care Products
陰性對照negative control
陽性對照positive control
賦形劑(excipitens).
穩定性 stability
生物利用度Biological Utilization
藥劑等效性, pharmaceutical equivalence
安慰劑, placebo
位點 site
受試者subject
成年男性和女性 male and female adults
為符合納入及排除標準的: 不能理解,抱歉,自己再改改吧!
BOP Bleeding on probing
頰側buccal ridge
舌側lingual
The fourth part: Testing criteriaof plaque reduction and gingivitis abating.
Application scope: This criteria is applicable for the products for plaque reduction and gingivitis abating, including toothpaste, mouthwash and other products.
Reference and criteria:
Clinical trials of plaque reduction and gingivitis abating
First: General principles
1. The products containing new active ingredients or systems
The effects of the products containing new active ingredients or systems for plaque reduction and gingivitis abating should be determined by two separate clinical trails.
2.The products containing the active ingredients determined by clinical trails
The effects of oral & dental care products containing the active ingredients and systems determined by clinical trails for plaque reduction and gingivitis abating should be tested the equivalence between the products to be checked and the positive control products which contained the same concentration of active ingredients after choosing proper gingivitis suffers, and also should set up negative control or placebo control group.
3.The effects of the products (such as toothpaste) containing various excipitens(inactive ingredients)which may affect the activity of plaque reduction and gingivitis abating should be tested by clinical trails.
4.The biological utilization and stability of the active ingredients in the blend should be provided with available testimony by the applicant.
Second: Research designs (randomization and control)
Generally the blind method、the stratified method, and the dual-unit parallel observation are used as clinical research methods.
Third: Testing period
The period need for the clinical trails of plaque reduction and gingivitis abating is fairly long. Generally it should be six months, and three clinical check at least (baseline, three months, and six months).
Fourth: Research objectives:
The subjects should be male and female adults suffered from gingivitis
Generally the subject number should be more than 30 in a complete trail.
Fifth: Checking index
1.The checking index should include acknowledged plaque index and the index which may reflect the gingivitis degree. The former includes plaque coverage (such as Quigley & Hein’s PLI modified by Turesky) or bacterium spot thickness (Silness & L?e’s PLI), stress on the observation of bacterium spots near and adjacent to the edge of the gum. If the above index is used, the reasons should be given. Record the degree of gingivitis expressed as bleeding index (BI) (Mazza), MBI, and BOP % (the percent of bleeding on probing sites to the total sites in the whole mouth after examination). The shape and color changing of gum edge and gum nipple could also be used as basic index, such as gingivitis index (GI). If other methods are used, they should have at least the same sensitivity as the above methods.
2.In principle, all the teeth in the mouth should be checked and recorded and six sites (Near-central of the buccal ridge, central of the buccal ridge, far-central of the buccal ridge, near-central of the lingual, central of the lingual, far-central of the lingual) or four sites (three sites of the buccal ridge and central of the lingual) of each tooth should be checked. The representative teeth shouldn’t be used(such as Ramfjord teeth, CPI teeth, etc).
Sixth: Issue and application of products
1.The effective ingredients and concentration of the products to be checked
should be the same as that of thepositive control products, other accessory ingredients should be the same or similar. Their appearance should be similar, if this requirement can not be achieve, then we can only fulfill the single-blind trail and issued the products by non-checkers.
2. Tell the subjects about the using requirement and the attention. We should do quantification as possible, the dosage of toothpaste (such as 1 cm long, 10ml mouthwash or one cover of the bottle/time), applied times daily, duration etc.
3.The conditions should be kept identical as possible except for the testing products. If the subjects use the same toothbrush, their original brushing habits might be kept. For the following reasons: ① Even though they are taught the uniform methods, not always every person can grasp and abide them; ② we should make the experiment similar to various people in their natural lives.
Seventh: Evaluation of effect
1.According to medical stat. Method, we analyze the variation of the whole-mouth mean values of every index of the treatment group and the control group respectively before and after the tests, then analyzes the index variations during every period between the two groups.
2. The evaluation of the effect should be determined according to the mean value variation and block comparison of each clinical index. And all the values and stat. Results should be listed in the report, The subjective evaluated criterion should not be used alone(high effective, effective, little effective, non-effective). In every clinical trail by comparison of the control group and the treatment group, every index reduction should meet the following conditions:[(Control-Treatment)/Control]≥15%。
從我收集的14萬個英語詞匯中篩選出帶vail的單詞有以下這些:
avail 效用,利益,幫助有用于,有助于
availability 可用性,可供貨
available 可利用的;可得到的;有效的
availably 可用地;可獲得地
availingly avail的變形
bioavailability 生物利用度;生物藥效率
bioavailable 生物及生物藥效應的
cavaillon卡維雍(法國地名)
countervail抵銷;補償;對抗
paravail 最低租戶
prevail 獲勝,流行
travail 職業勞動就業打工
trouvaille新發現,新發明;獨特的想法;意外所得
unavailable 不能利用的,不能獲得的
unavailing 無效的;徒勞的;無益的;無用的
unavailingly unavailing的變形
就這些,沒有了。
avail v. 有利于,有用 n.利益,效用
countervailv.補償,抵消
prevail v. 流行,獲勝
prevailing a. 普遍的,流行的
1、BA是BeautyAdviser的縮寫。意思是美容顧問。BA所指的就商場里化妝品專柜的美容顧問。容顧問有著豐富的產品知識和護膚技巧。不僅要銷售產品,還要針對不通的客戶皮膚,給出合理的意見,向其推薦適合她的產品。
2、Ba=barium,鋇,是一種化學元素。Ba比較常見的英文縮寫,有多種含義,比如:BA=BuildingAutomation,樓宇自動化,指國際化先進的樓宇設備管理;BA=BachelorofArts,文學學士等。
3、BA=bronchialasthma,是哮喘英文的簡稱,喘哮是由多種細胞特別是肥大細胞、嗜酸性粒細胞和T淋巴細胞參與的慢性氣道炎癥;在易感者中此種炎癥可引起反復發作的喘息、氣促、胸悶和咳嗽等癥狀。支氣管哮喘(簡稱:哮喘)是一種常見病、多發病。
擴展資料:
BA參與售前工作,為客戶提供業務咨詢以及需求引導,收集客戶需求并主導需求分析過程,參與設計應用方案,其主要工作:
1、參與售前工作,為客戶提供業務咨詢以及需求引導。
2、收集客戶需求并主導需求分析過程
3、參與設計應用方案。
4、提供最佳實踐指引,并指導客戶使用BI應用。
5、協助設計應用程序測試規則并進行測試。
以上就是生物利用度英文的全部內容,12、BA=Bioavailability,生物利用度,是指藥物被機體吸收進入循環的相對量和速率。 13、BA=Blood Agar,血平板。 14、BA model:1999年由Barabasi和Albert提出,是復雜網絡理論中的一種模型,即無標度模型(scale - free network model)。 15、BA=Business Analyst,需求分析師,業務分析師,IT行業的專業術語。